Starting from before its incorporation, the RASopathies Network USA has been a key player in bringing together families, clinicians and researchers to pool and build on the collective knowledge to maintain focus on RASopathy syndromes. RASopathies are a group of genetic syndromes that are as common as 1:1000. The RASopathy syndromes include: cardio-facio-cutaneous (CFC), Costello (CS), LEOPARD/NSML, Neurofibromatosis type 1 (NF1), and Noonan (NS).