HILTON HOTEL SAN DIEGO HOTEL Hilton San Diego Mission Valley puts you in the center of San Diego and within reach of the city’s most popular attractions, largest corporations, universities, and shopping centers in America’s Finest City. Located minutes away from the San Diego International Airport, near Hotel Circle, the Hilton San Diego Mission Valley provides access to all of the major freeways and is just minutes from both the San Diego Zoo and SeaWorld San Diego. Whether you are traveling on business, with friends, family, or solo, we welcome you to experience the Hilton San Diego Mission Valley. CLASSIC SOPHISTICATION. REFINED. The Hilton San Diego Mission Valley is elegant sophistication mixed with traditional touches of class can be found in every detail of the Mission Valley hotel. See photos Inside the Hilton San Diego Mission Valley, rich textures draped in dramatic soothing tones give each room and suite a sense of poised elegance. From regal gold accents, to modern metals and sumptuous wood, the Hilton San Diego Mission Valley bridges the gap between classic and contemporary with SoCal style. Deep colors, luxurious materials and world-class fabrics exude class and a home-like feel not found in most hotels. We invite you to experience a hotel like no other. Unparalleled guest services, a perfect location and contemporary styling makes the Hilton Mission Valley unlike any other San Diego area hotel.