The Baltic Biomaterials Centre of Excellence (BBCE) is established by three internationally recognized research institutions Riga Technical University (RTU), Latvian Institute of Organic Synthesis (LIOS), Rīga Stradiņš University (RSU) and clinical partner LTD “Rīga Stradiņš University Institute of Stomatology (RSU IS) operating in Latvia with a support from the international leading research institutes AO Research Institute Davos, Switzerland and Friedrich- Alexander University of Erlangen-Nuremberg, Germany, which main tasks in the project is support for research, research commercialization, knowledge transfer and management. Strategic research direction of BBCE is development of patient specific personalized solutions for bone regeneration in 3 levels: biomaterial composition, geometry and bioactive compound delivery. Full cycle of biomaterials for bone regeneration development consists of continuous steps: 1. Development of biodegradable, osteoconductive and osteoinductive materials, composites and drug delivery systems. 2. Preclinical in vitro/in vivo investigations. 3. Clinical trials.