Reproductive challenges currently affect 16-25% of all couples in the Nordics. Every 5th man never becomes a father, and every 10th woman has no or fewer children than she had hoped for. Infertility has been recognized as a disease by the WHO, but despite revolutionary developments in the techniques for assisted reproduction, the success rate per treatment, is still below 30%. ReproUnion is introducing a new research and innovation paradigm within reproductive medicine in Greater Copenhagen. The regional universities and hospitals are joining forces with leading international research institutes and companies, to solve five major global reproductive challenges, which are of great individual and social concern: Challenge 1: Improve human male fertility Challenge 2: Optimize reproductive health outcomes Challenge 3: Secure female ovarian function Challenge 4: Prevent infertility-related morbidity Challenge 5: Raise fertility awareness More than 50 professors and researchers in the ReproUnion partnership collaborate across borders and disciplines to drive research in the underlying reasons and optimized fertility treatments. The partnership also works on preventive initiatives to ensure that the society and young people are equipped with the right information to make informed choices about family planning. In 2020 we celebrate the 10-year anniversary of the Repro Collaboration and over this decade the partnership has developed a unique structure for cross-border collaboration, which positions Greater Copenhagen as a leading region in the effort to overcome infertility. Important goals for ReproUnion are to engage more key persons from international leading research environments & companies and establish long-term collaboration agreements with them as well as to identify sources of private and public funding. The partnership stands ready to bring reproductive research to the next level and look forward to connecting with new companies & research partners