The OMFS-IMPATH research group relates to development and validation of surgical tools and image-based solutions to advance in oromaxillofacial surgery, with an ultimate aim to obtain an optimised treatment outcome while minimizing the peri- and postsurgical risks, such as neurovascular trauma. In order to achieve this, a global integration of digital datasets will enable the creation of a virtual replica of the patient. This may allow full simulation of the surgery as well as of its expected outcome. While the latter may help to further modify and finetune the planned surgery, the former integrated virtual data may allow presurgical simulations, development of image-based surgical tools and navigation.