The ethical challenges posed by digital technologies span human activities from science to business to culture to politics. From concerns about the morality of genetic engineering to fears about the manipulation of public opinion via social media to legal debates about how to allocate the risk and responsibilities associated with artificial intelligence, these issues can often seem complex and impenetrable. Too often, we shrug our shoulders and abdicate responsibility, both personal and societal, for our collective actions in the digital realm. With the support of Lilly Endowment Inc., Indiana University, along with Purdue University, are developing integrated initiatives to better equip students and faculty to confront and address these ethical challenges presented by our digital world. With its breadth of scholarly resources, its interdisciplinary community, and its long history of engaging with ethics issues, Indiana University, along with its partners, can productively equip its students and faculty address with the challenges posed by new technologies, both now and in the future.