The Competence Center Machine Learning Rhine-Ruhr is one of six national nodes for bringing the development of Artificial Intelligence and Machine Learning in Germany to a worldwide leading level. To this end, we establish cutting-edge research and support young scientists. The research results of the Competence Center ML2R are directly used for practice-oriented applications. Particularly for small and medium-sized enterprises, ML2R offers access to strategies, knowledge and data and thus enables companies to successfully apply Machine Learning technologies. We connect pioneering research institutions in Germany: the TU Dortmund University, the Fraunhofer Institute for Intelligent Analysis and Information Systems IAIS in Sankt Augustin, the Fraunhofer Institute for Material Flow and Logistics IML in Dortmund and the University of Bonn. The close integration of basic and application-oriented research forms the ideal basis for innovation. We focus on the research fields: trustworthy ML, hybrid ML, resource-aware ML, and ML on Quantum Computers. In this way, we actively shape Germany’s future and contribute to securing the digital sovereignty of our country, because Machine Learning is the key to intelligent products, new business models and a head start in international competition. Follow us on Twitter: https://twitter.com/MLCompetence Our profile at ResearchGate: https://www.researchgate.net/project/Machine-Learning-Rhine-Ruhr-ML2R