Mackenzie Innovation Institute (Mi²) is positioned as a leader in healthcare applied innovation with a focus to ensure sustainability and long-term success. Mi² is a not-for-profit organization that focuses on creating and propagating sustainable change within Mackenzie Health, and to spread it more broadly at the healthcare system level. Mi² builds partnerships with industry, academia and government organizations and to establish system processes on implementation, usability, adoption and scalability of disruptive innovations, predominately in healthcare technology, but also in evidence-based practice changes and alternative service delivery and procurement models.