Our mission is simple, yet powerful: To cure Multiple Sulfatase Deficiency. Multiple Sulfatase Deficiency (MSD) is a rare genetic, fatal disease that affects children. Often described as "childhood dementia," MSD prevents the body from breaking down and filtering out the natural cellular waste that occurs in everyday cell functions. Children with MSD rarely survive past their 10th birthday. Currently there is no treatment or cure available for MSD, however there is hope. Various mutations of the SUMF1 gene are known to be the cause of MSD, and the knowledge of these specific gene mutations allows researchers and doctors to move forward and find a treatment and cure. Gene therapy could help slow the progression of the disease, and possibly deliver a cure. The United MSD Foundation is currently working with partner organizations, researchers, and doctors from all over the world to fund the first-ever clinical trial. Additional initiatives include continuing to identify patients worldwide, the development of a patient registry and advocating for newborn screening across the United States.