RADIUS is a multidisciplinary research group, dedicated towards sustainable chemistry based on insect and algae biomass. We perform research and can give advice on the cultivation of insects and microalgae, biorefinery, and computational modeling. Our microalgae research is done both on lab and pilot scale. As a pilot installation we have four closed tubular photobioreactors with a total volume of 4200L. We mainly focus on the optimization of cultivation conditions of biochemically interesting algae, to obtain high yield production processes of good quality material. The pilot plant reactors are installed in a greenhouse with an elaborate climate control system, so that the possibilities of cultivation of microalgae as innovative crop in horticulture can be examined. The greenhouse and photobioreactors are equipped with specialized measuring devices, so that it is well suited for practice-oriented research. We also study the economic feasibility and sustainability of the production of microalgae, like utilization of CO2 and wastewater, and the recycling of the culture media. In our insect facility we investigate how the breeding process of different insect species can be optimized. At the moment we have stable colonies of four insect species. Black soldier flies (Hermetia illucens), yellow mealworms (Tenebrio molitor), house crickets (Acheta domestic), and migratory locusts (Locusta migratoria). Apart from breeding optimization and the development of pilot scale production systems we focus on valorisation of organic side streams from industry and agriculture, and the quality and safety during insect breeding. Insects and microalgae contain interesting compounds such as proteins, fats, chitine, pigments, etc., which are valuable resources for applications in many different areas like food, feed and biobased chemicals. Together with different partners, our team also works on extracting these valuable components and finding new markets for these products.