Seven leading cancer centers have joined forces to form Cancer Core Europe—a European cancer association carrying out innovative research propelling cancer medicine into a new era. Cancer Core Europe builds upon the efforts of previous larger European consortia such as the EurocanPlatform, a project bringing together 28 European cancer institutions and organizations that was funded by the European Commission under the seventh framework program. Cancer Core Europe’s members are driven by a strong will to reshape the cancer research model to ultimately increase the European Union’s competitiveness as a place to conduct cutting-edge research that’s translated to the clinic to deliver more personalized medicine.