Trusted evidence. Informed decisions. Better health. Cochrane is a global independent network of researchers, professionals, patients, carers and people interested in health. We are a not-for-profit organization with contributors from all over the world, working together to produce credible, accessible health information that is free from commercial sponsorship and other conflicts of interest. We do this by producing reviews that summarize the best available evidence generated through research to inform decisions about health. Cochrane UK is one of many regional centres and branches supporting the global work of Cochrane and maximizing the use and impact of Cochrane Reviews for the UK and Ireland. Cochrane UK is funded by the National Institute for Health and Care Research (NIHR) and hosted by the Oxford University Hospitals NHS Trust. The centre supports the production of Cochrane Systematic Reviews through a Learning and Development Programme for Cochrane authors and other contributors. We aim to maximize the impact of Cochrane Reviews by disseminating the findings widely to health professionals, researchers, commissioners, the public, charities and the media, through social media, events, presentations and partnerships through our Engagement Programme. Cochrane Reviews are widely used to inform healthcare guidance, best practice guidance in primary care and patient decision aids in shared decision-making initiatives. In the UK, for example, Cochrane Reviews are used to inform the National Institute for Health and Care Excellence (NICE) and the Scottish Intercollegiate Guidelines Network (SIGN) guidelines, NICE Clinical Knowledge Summaries and NHS Shared Decision Making – patient decision aids. The reviews also form an important source of knowledge within the NHS Evidence portal, supported by NICE.