ITCC gathers 63 European Paediatric Oncology Departments with expertise in conducting early phase trials in children and adolescents, and 25 European research laboratories. The aim of this organisation is to develop novel therapies for the treatment of paediatric and adolescent cancers in cooperation with regulatory bodies, pharmaceutical enterprises, parents and patients. In January 2011 ITCC was established as a European Category 1 Network for Paediatric Research at the European Medicines Agency (EnprEMA). Its structure comprises several Committees which take care and contribute to a particular issue in the development of novel therapeutic strategies in paediatric oncology.