The area of interest of our research group, Clinical Pharmacology and Pharmacotherapy, is the safe and efficient use of medicinal products – including small molecules, biologicals and vaccines – in humans. In our clinical pharmacology studies, most frequently in early stage development, mainly healthy subjects or well-defined patient populations are involved. In our regulatory science research, we focus on a) the design and conduct of clinical trials (linked to the Clinical Trials Centre of the University Hospitals Leuven); b) regulatory and legal aspects of medicinal product development, intellectual property rights; and c) health economic aspects of medicinal products (economic evaluation of medicinal products, policy relating to market access of medicinal products). In our pharmacotherapy studies, the focus is on the use of medicinal products in daily patient care (both ambulatory and in a hospital setting), while in our pharmaceutical care/clinical pharmacy studies, we explore the role of the pharmacist in the rational use of medicinal products in the ambulatory setting (pharmaceutical care) as well as in the hospital (clinical pharmacy). In summary, our research group offers state-of-the-art expertise from first-in-man studies up to commercialization, intellectual property issues and regulatory steps included, and the subsequent daily use of medicinal products in an ambulatory or hospital setting. This expertise is open for academic (i.e. intradepartmental, interdepartmental and inter-university), governmental/regulatory and industrial collaborations.