Atlantic Bone Screen is a leading CRO (« Contract Research Organization ») specialized in high-quality preclinical evaluation services in the field of bone and joint diseases and more particularly in bone diseases from tumor origin. Thanks to its high expertise, Atlantic Bone Screen also evaluates biomaterials, either for orthopedic or dental applications. We provide high-quality services to support the characterization of drug candidates, nutraceuticals, biomaterials,... Located in Nantes, North-West of France and created in 2005 by Ronan LE BOT, CEO of the company, Atlantic Bone Screen puts at your disposal a unique preclinical platform with a wide range of assays: - In vitro assays: Primary cells and cell lines from human and/or animal origin: osteoclasts, osteoblasts, macrophages or chondrocytes, tumor cell lines - In vivo assays: Reliable animal models (rats, mice, rabbits, sheeps) reproducing human bone pathologies (Osteoporosis, Arthritis, Osteosarcoma, Ewing sarcoma, mammary carcinoma, lung metastases) / we have our own animal facilities - Histology/Histopathology (hard and soft tissue) : * Embedding (paraffin, resin, frozen) * Chromogenic staining and Immunostaining of tissue markers (IHC and IF) * Histopathology and image analysis (tissue parameters or components) * Multi-organ toxicity studies, experimental model analysis,… - Imaging services: microCT, and X-Ray analyses Get in touch with us for additional information and request! And also discover our Sister Companies: - ATLANCHIM PHARMA, custom chemical synthesis CRO - www.atlanchimpharma.com - ATLANTHERA, drug discovery company in bone research - www.atlanthera.com