The Innovation and Value Initiative (IVI) engages a broad coalition of providers, payers, patient advocates, scientists, researchers, and others who are dedicated to preserving innovation and enhancing value across the healthcare system. IVI works to create common approaches for relevant, rigorous, and transparent value assessments in healthcare by identifying, supporting, and disseminating best practices. IVI is founded in belief that an informed and dispassionate dialogue around value assessment is essential to the future vitality of the American healthcare system. We hope to fuel that dialogue with timely, non-biased, and well-focused research, evidence, and analysis.