SITS International is an academic-driven, non-profit foundation and international collaboration with a base at Karolinska Institutet in Sweden. It is an initiative by the medical profession to accelerate clinical trials and to certify excellence in acute and secondary prevention stroke treatment. SITS Network includes over 2500 medical professionals in +70 countries around the world. SITS Registry include treatment data from more than 140.000 patients suffering from acute stroke. SITS Registry and Network structure provides benefits for all key stakeholders. These include patients, researchers, heads of clinics, regulatory bodies, and pharmaceutical companies. - Patients receive quicker access to leading stroke treatments and are assured of safety follow-ups, - Researchers get the opportunity to join the Networks to strengthen research within their geographical region, get access to internationally renowned researchers and given opportunities to be part of high-impact studies. The use of SITS IV Thrombolysis and Thrombectomy Registries are free of charge. - Heads of clinics are in many cases using the SITS Registries as a tool for treatment follow- up and comparison to best practice, such as door-to-needle time. - As a research partner SITS International may offer customised registry based studies and advise on what data to collect to answer scientific questions through our well renowned scientific committee. Today there are about 50 published articles based on SITS Registry data in international peer-reviewed journals such as The Lancet, Lancet Neurology, BMJ, Annals of Neurology, Stroke, JAMA Neurology etc. More than 150 co-authors have contributed to these articles. SITS International is financed through a variety of European research grants, sponsorships from pharmaceutical companies, and other individuals. It is significant to SITS International foundation to maintain a good balance between different types of grants/sponsorships.