The growing need of reliable vehicle simulations for safety and performance improvement is leading academy and industry to carry out researches aimed at proposing innovative solutions able to guarantee the achievement of real-time, robust and predictive physical vehicle and tire models. MegaRide project is tightly linked to the activities carried out by the Vehicle Dynamics research group of the Department of Industrial Engineering (DII) of University of Naples Federico II, whose expertise is oriented to the development of models and procedures to be employed by vehicle manufacturers, tire developers, dynamicists and race engineers. MegaRide’s core is made of people working in a synergic environment involving both academic and industrial realities. The team diverse experiences and careers have been characterized by deep cooperation with high-profile companies and research centres. Services and products provided by MegaRide are based on an already thriving trade, structured thanks to many years of research partnerships between the research group and relevant automotive realities. MegaRide was born as a natural outcome project, thought to confer the proper value to the products of the Italian scientific research and to reinforce the still unexpressed potential of valuable academic realities. The company headquarter has been set in the Mechanics building of the Department of Industrial Engineering, where the UniNa Tyre Lab is located, in order optimize the information transfer and the logistics operations between the two institutions. At the current stage MegaRide has received, after a demanding evaluation process, the approval of the University of Naples committee for the official Spin-Off recognition.