The Michigan Radiation Oncology Quality Consortium (MROQC) was established in 2011, through the generous support from Blue Cross Blue Shield of Michigan and Blue Care Network. In this first-of-its-kind collaborative quality initiative (CQI), MROQC has created a comprehensive clinical data registry of patients receiving radiation treatment for breast, lung, and prostate cancers and bone metastases. Our registry is maintained by the MROQC Coordinating Center and includes both patient-reported outcomes and physician assessments of toxicity as well as data on radiation treatment delivery and dose.