Indian Institute of Integrative Medicine (IIIM) is a national Institute of the Council of Scientific & Industrial Research (CSIR) of India. The mandate of IIIM is to be an internationally competitive centre of excellence in all facets of natural products research and technology, including (a) discovery of novel pharmacologically active natural products from plants and microbial species and translating them into drug leads and candidates by medicinal chemistry, preclinical pharmacology and clinical development. This approach is pursued both in NCE as well as botanical herbal mode; (b) Preclinical and clinical validation and establishment of mechanism of action of drugs used in various Indian systems of Medicines (Ayurveda, Unani, Siddha and other Indigenous systems of medicine); (c) develop agro-technologies and commercial cultivation of high value medicinal and aromatic plants from Western Himalayas including Kashmir Valley and Laddkh for national and international markets; and (d) to work with Indian and global pharmaceutical industry to out-license new products and technologies.