The Cluster »Matters of Activity. Image Space Material« aims to create a basis for a new culture of materials. The central vision of the Cluster is to rediscover the analog in the activity of images, spaces and materials in the age of the digital. Biology and technology, mind and material, nature and culture intertwine in a new way. In this context, the interdisciplinary research and development of sustainable practices and structures is a central concern in areas such as architecture and soft robotics, textiles, materials and digital filters, and surgical cutting techniques. In six projects, more than 40 disciplines systematically investigate design strategies for active materials and structures that adapt to specific requirements and environments. The Cluster focuses on a new role of design, which is emerging in the context of growing diversity and the continuous development of materials and visualization forms in all disciplines.