Neuroplasticity – the ability of the brain and spinal cord to health itself – has changed the way we understand the nervous system and disorders affecting it. Contrary to longstanding teachings in neuroscience we now know that the brain and spinal cord are capable of finding new pathways and new ways of working such that people can regain valuable function and quality of life. I CAN! will provide clinical, educational and research services based on neuroplasticity principles focusing on this new paradigm for people with neurodisability. It will utilise innovative models of care, teaching and research to empower people with serious disability of the brain and spine, research the state of the art of care, and educate health and disability professionals in the principles of neuroplasticity.