Isfahan Cardiovascular Research Institute is a WHO collaborating center for research and training in cardiovascular disease (CVD) control, prevention, and rehabilitation for cardiac patients in the Eastern Mediterranean region (EMR). ICRI initiated its activities in 1987 with aiming to perform research on CVD prevention and public health promotion. The central goal of ICRI is to utilize the existing technology to performing community-oriented biomedical research, producing applicable results, and contributing to furthering human knowledge in the realm of medical science. ICRI Consists of the following research centers: Isfahan Cardiovascular Research Center (CRC) Hypertension Research Center (HRC) Cardiac Rehabilitation Research Center (CRRC) Heart Failure Research Center (HFRC) Interventional Cardiology Research Center (ICRC) Pediatric Heart Research Center (PHRC) Applied Physiology Research Center (PRC)