TeethCloud is a collaborative of clinicians, educators, researchers, and students from 31 nations who strive constantly to improve health around the world through innovative Dental Informatics. Together they form a virtual think tank of expertise which facilitates answers to the challenges and opportunities to decrease global oral health inequalities. Making research and information more accessible, useful, and placed in the hands of patients and professionals alike, TeethCloud assembles and empowers informaticists who believe that data drives evidence-based decisions which lead to meaningful, measurable, and positive outcomes for dentistry and oral health in the 21st century.