Slope provides an online eClinical Supply Chain Management (eCSCM) platform for sponsors and research sites collaborating on complex, sample-intensive, early-phase clinical trials. The Slope eCSCM platform reduces clinical trial risks, reigns in costs, improves the productivity of clinical trial collaborators, and increases subject retention by moving the manual, spreadsheet-driven, and error-prone processes used to manage and track clinical supplies and biological samples to a digital platform. Through its 21 CFR Part 11-compliant platform and protocol-specific guided workflows, Slope fosters collaboration between sponsors, sites, suppliers, labs, biorepositories, and couriers; provides real-time visibility into activities at research sites; ensures traceable chain-of-custody for supplies and samples in use, transit, and storage; and contributes to stronger compliance. To date, Slope has managed over a million supplies for thousands of studies across hundreds of sites. Slope transforms intricate study protocols into software-guided workflows, capturing clinical supply chain demand data at the patient level to drive Slope’s on-demand kitting services and auto-replenishment workflows, ensuring clinical research sites always have exactly what they need for inbound patients, and that every job gets done.