The purpose of the UT Austin Portugal Program is to promote new frontiers of knowledge in strategic themes, through the advancement of high-level education, research, and commercialization activities. The UT Austin Portugal Program is a partnership program in Science and Technology between the Portuguese Foundation of Science and Technology (FCT) and the University of Texas at Austin (UT Austin), supported by the Ministry of Science, Technology, and Higher Education in close collaboration with the Council of Rectors of the Portuguese Universities (CRUP). Launched in 2007, the partnership is renewed in 2018, towards a new decade until 2030. After ten years of joint collaboration, UT Austin and Portuguese institutions continue to develop a cooperative effort to promote a thriving research agenda, strongly aligned with the strategy of the country in the different scientific and technological areas. The program seeks to stimulate and reinforce the effective collaboration among researchers, faculty, students and companies through collaborative R&D projects and high-level education and training opportunities, while promoting and enabling a deeper involvement in the multidisciplinary network between Portugal and Austin. Simultaneously, the engagement of technology firms and new entrepreneurial initiatives should continue and be reinforced through the University Technology Enterprise Network (UTEN), to prepare Portuguese researchers and innovators for scientific readiness for commercialization success.