We need to re-evaluate the way we think about machines. Disruptive technologies of modern artificial intelligence open up completely new applications and business models. In combination with the unbeaten creative power of humans, ethically correctly applied, this will provide a prosperous future for us all. Deep-learning and big data is probably the key driver of the fourth industrial revolution. The opportunities but also the complexity of smart manufacturing has reached unexpected heights. Integrating the support and input of various disciplines is more important than ever. We are ready.