The Institute for Bio-Economy and Agri-Technology (iBO), a non-profit research and technological development organization, is from 2013 one of the five Institutes of the Center for Research and Technology – Hellas (CERTH) administered by the Ministry of Education, Religions Affairs and Long Life Learning. In the integration process within CERTH, iBO is redeployed generating a new identity oriented to the agri-technologies and bio-systems engineering scientific domains by integrating the existing scientific niches and research units orchestrated towards one scope. iBO philosophy lays on a multiple-disciplinary approach toward the development and advancement of technologies dedicated to the bio-production systems domain, including crop production, livestock, and fisheries, under the external framework of economic development, welfare, and environmental impact alleviation, while in parallel it generates new technological paradigms shift for other domains.