Founded in February 2019, we are an organization of health professionals and scientists who care about stroke and other cerebrovascular diseases in childhood. We developed out of our original collaborative network, the International Pediatric Stroke Study (IPSS), and now aim to broaden the scope of our mission beyond research. IPSO is bringing together leading investigators and health professionals from around the globe, and from multiple disciplines, with a common interest in childhood cerebrovascular disease. Experts across related fields will collaborate to advance knowledge on mechanisms of childhood stroke and stroke recovery with an eye towards preventing stroke and improving outcomes. IPSO will disseminate knowledge and best practices to first-line medical providers for the wider benefit of children with stroke worldwide. Throughout, IPSO will engage affected families to set priorities and advocate for children at risk for stroke or afflicted by stroke.