The Health Finance Institute (HFI) is a US-based non-profit organization that aims to design, catalyze, test, and scale novel financing instruments and pathways for noncommunicable diseases, or NCDs (diabetes, heart disease, cancer, chronic obstructive pulmonary disease, and mental health), with an ultimate goal of accelerating the expansion of fiscal space for NCDs globally. At the heart of HFI’s mission is that nobody chooses disease, as research shows that NCDs stem from a range of environmental and societal, social determinants, and biological factors, and HFI recognizes the severe economic burden that NCDs have on a global economy. Non-communicable diseases (NCDs) are the leading cause of death and disability, globally. Yet, there continues to be an under investment in action and health financing by the global community. HFI’s vision is simple: to implement robust, evidence-based innovative funding mechanisms to broker partnerships across public and private sectors and leverage unique expertise across health and finance to close the current gap in funding for NCDs. As the COVID-19 infection rate climbs globally, HFI is uniquely positioned to call attention to a deeper understanding of the populations that are most at risk for severe infection and mortality due to COVID-19. HFI’s rapid response to the COVID-19 epidemic presents an opportunity not to alleviate the current burden facing health and financial systems, but also to build awareness of the potential impact of NCDs on future infectious disease outbreaks. The expert HFI team brings together decades of experience in health economics, tracking development assistance for health and non-communicable disease, clinical care, health finance, health reform, universal health care reform, project implementation, and working in all sectors: government, international organizations, non-profit and civil society, the private sector, and academia.