App&Town is an accessible application for mobile devices with Android and iOS operating systems that guides from a point of origin to a destination by using of metropolitan transport. Given a destination, the application offers a set of optimal paths to choose from. Having chosen one, the application guides the user from the point where he or she is to the bus stop. At this point, the system informs the user of the time left for the bus to get there. Once on the bus, the user will receive information from the bus stops he or she goes by and advised of when to press the buzzer to get off at the next stop. When the user has got off, he or she is guided to the destination. If no bus is needed, then the user will be guided walking. It is an ambient intelligence application in the urban environment using the latest technologies available on mobile devices such as GPS, compass and accelerometer, as well as 3G or WiFi connection to provide maps and a guidance system in a friendly environment. The application has been developed following the 7 principles of universal design to achieve full accessibility. It is multi-modal, multi-language and extensible to different cities.