1. Dementia/Alzheimer's disease Target disease: Alzheimer's disease 2. Peripheral amyloidosis Target disease: Cardiac / renal amyloidosis 3. New DDS system and therapeutic drug development Target disease: Target disease: Alzheimer's disease 4. Infectious disease Target disease: Infectious disease including Corona-virus (SARS-CoV-2) 5. Cancer immunity-related therapeutics (except PD-1, PD-L1) Target disease: Target disease: Solid cancer