Nested in the Department of Industrial and Systems Engineering at the University of Tennessee, the Center for Advanced Systems Research and Education (CASRE) is a multifaceted research and education center dedicated to the advancement of operational excellence systems that serve the ever-increasing complexities of our society. Experts in various systems specialties including operational excellence, lean, six sigma, optimization, simulation modeling, statistical analyses, and machine learning, integrate CASRE. It engages industry practitioners that seek to improve the company’s systems and their own expertise while discussing shared improvement opportunities.