pxlence (pronounced 'pixellence') is a Ghent University spin-off company founded in 2015 by Dr. Steve Lefever, Prof. Frauke Coppieters and Prof. Jo Vandesompele with an exclusive commercial license for PCR based target enrichment technology from Ghent University. Using the state-of-the-art high-throughput primer design software pipeline primerXL, almost one million assays for amplification of DNA from both fresh frozen and formalin fixed parafin embedded (FFPE) material covering over 99% of the human exome were expertly designed. These best-in-class assays enable the enrichment of any exonic region of interest for targeted resequencing or for confirmation of variants by means of Sanger or next-generation sequencing. More than 6500 individual assays for 500 genes have been tested in a diagnostic setting (ISO 15189) with a wet-lab success rate exceeding 95%. In 2020, the Human Sample ID Kit was released, a DNA sample tracking solution using a 50 SNP multiplex PCR and proprietary closed single-tube library preparation technology. Our customers include clinical diagnostic labs, genetic centers, hospitals, and diagnostic or medical device companies in the field of PCR based target enrichment.