Clinical pharmacists can identify and address gaps in patient-self care including medication adherence and compliance, disease state management, and preventative measures such as immunizations and smoking cessation. Many patients with chronic conditions receive care from several providers leading to fragmented care. Pharmacists can coordinate care and provide clinical expertise relating to drug efficacy, safety, drug-drug interactions, disease-drug interactions and new clinical guideline recommendations. In providing a broader clinical picture as it relates to pharmacotherapy and assisting patients directly with medication related problems, pharmacists can improve both quality and safety measures impacting patient care.