Alfieri Heart Foundation was established in 2018 on its founder’s will, Prof. Ottavio Alfieri, with the aim of promoting innovation, research, development, thanks to focused and well-defined projects, to be implemented in a multidisciplinary and highly specialized environment, in the fight against heart diseases. Heart diseases are one of the main causes of mortality and disability. They have a devastating effect on the individual, not only from a physical point of view but, most of all, also for the discouragement and depression they create. For these patients there is a lot to do (more than we do today) by researching and implementing appropriate, innovative and avant-garde, technically advanced, highly personalized treatments, that respect individual peculiarities. Alfieri Heart Foundation carries out its activities thanks to the contribution of private individuals and partner companies that share research and training values and choose to support it in many different ways. This is a very ambitious project in collaboration with the world of education, research and entrepreneurship and the Foudation will pursuit it, thanks to its main driver: passion, concreteness and professionalism.