The MGH/HST Martinos Center for Biomedical Imaging is a leader in translational research with and development of a host of state-of-the-art imaging technologies. Its faculty include world-class experts in disciplines spanning the basic biosciences and clinical investigation. The backbone of the Martinos Center is the Imaging and Computational Core Resources. The Imaging Cores include the MRI, MEG and Optical Imaging Cores, with an extensive and expanding inventory of state-of-the-art imaging facilities and equipment, including related laboratories and testing rooms. The Computational Core oversees data processing, computational infrastructure, software and hardware issues. Together, the Imaging and Computational Cores develop and provide state-of-the art biomedical imaging and image processing technology and techniques to the Center's research faculty and user community.