Health Sciences South Carolina (HSSC) is an inclusive public-private organization that brings together research universities, health systems, and other partners to further clinical research, population health, quality, and data exchange initiatives. Founded in 2004 as the nation's first statewide health data and research collaborative, the members of this unique consortium include the state’s largest research-intensive universities (Clemson University, the Medical University of South Carolina, and the University of South Carolina) and six of the state’s largest healthcare systems (AnMed Health, McLeod Health, Medical University of South Carolina Hospital Authority, Palmetto Health, Self Regional Healthcare, and Spartanburg Regional Healthcare System). HSSC was established with the vision of transforming South Carolina’s public health and economic wellbeing. HSSC also provides financial support to 12 South Carolina Centers of Economic Excellence, which are led by world-class researchers. Research conducted in these centers is leading to new products and services with the potential to improve public health while creating economic development opportunities and new jobs in the state.