Lowe Syndrome is a genetic disorder that can occur with no family history, affecting boys and multiple physical and mental handicaps including cataracts, muscle weakness, kidney problems, cysts, brittle bones, arthritis, poor growth, mental impairment with behaviour problems (autistic spectrum disorder) and epilepsy. The Lowe Syndrome Trust is a UK Charity formed in 2000 by parents of a Lowe syndrome child. The charity supports families and initiates and funds medical research into Lowe Syndrome. Our goal is to initiate, fund and encourage medical research which will hopefully lead to the development of drugs to better regulate the metabolic imbalance of Lowe’s and eventually a cure. We also provide information and support for families whose children have been affected by this condition.