SafeTRANS ("Safety in Transportation Systems") is a Competence Cluster combining research and development expertise in the area of complex embedded systems in transportation systems (automotive, avionics, rail, and maritime) and further safety-critical domains. SafeTRANS supports its members in the preparation and harmonisation of research and development strategies, summarises the strategies in roadmaps and anchors identified priority topics in national and European funding programs. In addition to strategic activities, SafeTRANS fosters project incubation on national and European level, e. g. through consortium building, selection of topics, and help in the application process. The sustainability of project results and its industrial use are supported by a so-called research eco systems.