The Cardiac Safety Research Consortium (CSRC) provides leadership and guidance for regulators, public and private clinical researchers through an open, interactive forum to collectively address cardiovascular-related issues in clinical trials for both new and existing products. The organization offers unique resources and a collaborative structure that allows for valuable contributions to scientific study design, data analysis and interpretation and dissemination to the public. One of the defining characteristics of effective leadership is creating a structure that embraces collaboration to produce tangible outcomes and provides a path forward to improve the lives of patients. CSRC works with numerous key stakeholders, clinical research organization partners, and clinical researchers to identify cardiovascular safety barriers to therapeutic innovation and develop pragmatic, innovative solutions to overcome those barriers. The impact of CSRC and the thought leadership of its members on key cardiac safety research issues has a proven track record of benefiting the global scientific and regulatory community. Follow us on Twitter at @CardiacSafety to learn more about our impact and opportunities for engagement.