ACE AI Lab is an initiative by Amsterdam Center for Entrepreneurship (ACE), the academic incubator of Amsterdam. The mission of the lab is to empower entrepreneurial academics in the Netherlands to launch their AI-based startups. This is achieved via collaborations with industry partners, healthcare and governmental organizations, which provide use-cases that are valuable for their business and for which an AI-solution is a good fit. These use-cases are then picked up by entrepreneurial academic teams, who within a 3-month program, build a proof-of-concept of the solution and lay the basis of their future AI startup. With a hands-on venture building approach, coaching by experienced AI-entrepreneurs, and access to domain experts, approximately 40% of the academic teams go on to establish an AI-startup.