Securing America’s Medicines and Supply (SAMS) is a multi-industry coalition of companies with the mission to strengthen the security of the medical supply chain in the United States. SAMS seeks to drive implementation of legislation and regulation to reward and foster U.S.-made manufacturing of important pharmaceutical products, devices, and personal protective equipment. SAMS supports U.S. patients, domestic healthcare security, and U.S. jobs. Specific policy initiatives include: 1.Encourage increased manufacturing operations within U.S. borders for the U.S. medical supply chain via reforms to trade and tax law to design policies that promote domestic production. 2. Maintain and expand U.S. government loan, grant, direct investment, and purchase agreement programs for important medical infrastructure developed by companies primarily manufacturing in the United States through the National Institutes of Health (NIH) and Biomedical Advanced Research Development Authority (BARDA). 3. Explore opportunities within Medicare, the Veterans Administration, and the Department of Defense to recognize and promote U.S.-made pharmaceutical products and supplies. 4. Strengthen procurement to the strategic national stockpile (SNS) for important pharmaceuticals, diagnostics, medical devices, and personal protective equipment, with emphasis on those produced domestically.