Metabolic Profiling Research Group (MPRG) was founded in April 2006 by Prof. Eric Chun Yong CHAN, National University of Singapore, Department of Pharmacy. Research Focus 1. Metabolism-driven systems biology modeling of diseases, pharmacology, toxicology and mammalian host-bacteria interactions. 2. Xenobiotic-derived reactive metabolite research with specific focus on interaction with biological proteins, regulation of metabolic pathway, protein post-translational modification and physiological-based pharmacokinetics-pharmacodynamics (PBPK-PD) modeling of pharmacology and toxicology.