NUS Synthetic Biology for Clinical and Technological Innovation (SynCTI) was formally established in Jan 2015 as the focal research program for synthetic biology at the National University of Singapore. SynCTI operates as a highly interdisciplinary research core that amalgamates leading Principal Investigators from Yong Loo Lin School of Medicine, the Faculty of Science and the Faculty of Engineering. Through research collaborations with renowned international institutes and private industries, SynCTI strives to create new knowledge and develop foundational technologies in synthetic biology and groom future generations of highly skilled researchers endowed with basic science and translational research capabilities.