The NeuroPoint Alliance (NPA) is a 501(c)(6) subsidiary nonprofit organization of the American Association of Neurological Surgeons (AANS). The NPA was established in 2008 to improve the quality of neurosurgical care through the acquisition, analysis and reporting of clinical data via registries and related studies. The NPA is designed to meet the quality improvement and research needs of physicians and allied health care professionals, health care plans, the biomedical industry and government agencies. To accomplish this, NPA spearheads and manages various clinical data registries and studies. Clinical data registries are valuable tools to support evidence development, performance assessment, comparative effectiveness studies and adoption of new treatments into routine clinical practice.