MediSphere is an independent, dedicated clinical research center which conducts Phase II, III and IV clinical research for pharmaceutical, biotechnology, nutritional, and medical device industries. Founded in 1992, MediSphere has participated in more than 600 national and multinational clinical trials. MediSphere has more than 25,000 active patient files in Evansville, IN, the major city in the Tri-State area. The Tri-State, with a population of 1.2 million, is composed of 11 counties in Southwest Indiana, Western Kentucky and Southeast Illinois. MediSphere is a member of the Alliance for Multispecialty Research (AMR), an independent Site Alliance (ISA) of established, geographically diverse, professional clinical research sites. This not-for-profit support organization is composed of 20 multi-therapeutic, highly experienced research centers across the United States.