Microsin SRL is the only Romanian manufacturer of pharmaceutical active ingredients. The company was built on 20 May 1991 by Eng. Ioan Gârbea, who at that time had 25 year-experience in research and in the development of pharmaceutical active ingredients. Its activity began in a building rented within Sicomed factory premises (currently Zentiva-Sanofi). In September 2006, the management finished the building of a production unit for pharmaceutical active ingredients compliant with EU-GMP regulations. The company is fully equipped for the production of active pharmaceutical ingredients under EU-GMP regulations. There are two production lines. The first ends with a fluid bed dryer with a capacity of 250 kg, while the second ends with a with a fluid bed dryer with a capacity of 500 kg. The manufacturing area, having a surface of 480 sqm, consists in 33 stainless steel and enamel reactors, with capacities between 400 and 6000 liters. The facility is also equipped with 8 centrifuges, 4 tray dryers and distillation columns for solvents recovery, etc. The manufacturing process makes use of purified water obtained with the help of an inverted osmosis and de-ionizing device. The clean area, with a surface of 200 sqm is classified as ISO 7.