The Trans-Atlantic Business Council (TABC) is a cross-sectorial business association representing companies headquartered in the EU and U.S. that serves as the main business interlocutor to both the U.S. government and the EU institutions on issues impacting the transatlantic economy. The transatlantic partnership is faced with increasing challenges, including the rise of nationalism and economic populism that threaten the liberal democratic principles, market integration, and international trading arrangements built under EU and U.S. leadership over the past 70 years. Globalization itself is being questioned on both sides of the Atlantic, as is the free flow of data across borders that is fundamental to global commerce. Sustained transatlantic leadership, including by the business community, is paramount to address these challenges and reinforce common Western principles. As integral participants in the transatlantic economy and its local communities, EU and U.S. businesses have an important role to play. TABC exists to promote and enhance transatlantic economic integration and strengthened political ties between the EU and U.S., while reinforcing the role of business as a major stakeholder in various EU-U.S. official dialogues. TABC provides the only platform for European and U.S. companies to work jointly to improve transatlantic collaboration in areas such as ICT, energy, research, innovation, intellectual property, and TTIP negotiations through the development of and advocacy for constructive recommendations and transatlantic solutions. Such business engagement is now more important than ever.