The Global Liver Institute (GLI) is the collaboration and innovation platform for the liver community worldwide. The GLI serves the liver community by: (1) Increasing the voice for liver issues in the global public health conversation; (2) Facilitating collaborative approaches and knowledge–sharing among patient advocates, policymakers, regulators, public health officials, clinicians and researchers in liver disease and therapeutic areas relevant to liver disease (e.g. HIV, IBD, cancer) and (3) Attracting and highlighting innovation, particularly digital/technical innovation, to challenges faced by liver patients.